Rochester is a city in southern Minnesota. It’s the birthplace of renowned healthcare organization the Mayo Clinic. The complex includes the landmark 1928 Plummer Building. On the outskirts, Mayowood is the 1911 estate of clinic co-founder Dr. Charles Mayo. The early-20th-century Plummer House has period furnishings and sprawling grounds. Rochester Art Center has contemporary art shows and views of the Zumbro River.